Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The association between N-acetyltransferase 2 gene polymorphisms and pancreatic cancer.

Cell biochemistry and function - 1 Apr 2008

Ayaz Lokman, Ercan Bahadir, Dirlik Musa, Atik Uğur, Tamer Lülüfer

Abstract excerpt

Pancreatic cancer has been linked with exposure to environmental chemicals, which generally require metabolic activation to highly reactive toxic or carcinogenic intermediates. N-acetyltransferase 1 (NAT1) and N-acetyltransferase 2 (NAT2) are expressed primarily in extrahepatic and hepatic tissues, respectively. Both enzymes catalyze N- and O-acetylation of aromatic and heterocyclic amines. It is believed that...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Arylamine N-Acetyltransferase
Share to Case-Control Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to NAT1 gene

Share to NAT2 gene

Share to Genetic Predisposition to Disease

Share to Pancreatic Neoplasms

Share to Phenotype

Share to Polymorphism, Genetic

Source

Identifiers

PMID: 18027363
DOI: 10.1002/cbf.1445

Genes

NAT2
NAT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The association between N-acetyltransferase 2 gene polymorphisms and pancreatic cancer.PMID 18027363Read ↗

Association between N-acetyltransferase 2 polymorphisms and pancreatic cancer risk: a meta-analysis.Semantic proximity Read ↗

Polymorphisms of cytochrome P4501A2 and N-acetyltransferase genes, smoking, and risk of pancreatic cancer.Semantic proximity Read ↗

Molecular genetics and epidemiology of the NAT1 and NAT2 acetylation polymorphisms.Semantic proximity Read ↗

Haplotype of N-acetyltransferase 1 and 2 and risk of pancreatic cancer.Semantic proximity Read ↗

Association of genetic polymorphisms of N-acetyltransferase 2 and susceptibility to esophageal cancer in north Indian population.Semantic proximity Read ↗

Polymorphic NATs and cancer predisposition.Semantic proximity Read ↗

Genetic polymorphism of N-acetyltransferases, glutathione S-transferase M1 and NAD(P)H:quinone oxidoreductase in relation to malignant and benign pancreatic disease risk. The International Pancreatic Disease Study Group.Semantic proximity Read ↗

N-Acetyltransferase genetics and their role in predisposition to aromatic and heterocyclic amine-induced carcinogenesis.Semantic proximity Read ↗

N-acetyltransferase 2 phenotype and risk of esophageal cancer: a meta analysis.Semantic proximity Read ↗

Molecular genetics and function of NAT1 and NAT2: role in aromatic amine metabolism and carcinogenesis.Semantic proximity Read ↗

N-acetyltransferase 2 gene polymorphisms are associated with susceptibility to cancer: a meta-analysis.Semantic proximity Read ↗

Genetic polymorphism of N-acetyltransferase 2 in patients with esophageal cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.