Article
Superoxide dismutase and nicotinamide adenine dinucleotide phosphate: quinone oxidoreductase polymorphisms and pancreatic cancer risk.
Pancreas - 1 Jan 2011
Mohelnikova-Duchonova Beatrice, Marsakova Lenka, Vrana David, Holcatova Ivana, Ryska Miroslav, Smerhovsky Zdenek, Slamova Alena, Schejbalova Miriam, Soucek Pavel
Abstract excerpt
OBJECTIVES: Pancreatic carcinoma etiology and molecular pathogenesis is weakly understood. According to the assumption that genetic variation in carcinogen metabolism further modifies the risk of exposure-related cancers, an association of functional polymorphisms in oxidative stress-modifying ge...
Topics
- Adult
- Aged
- Female
- Genetic Predisposition to Disease
- Humans
- Male
- Middle Aged
- NAD(P)H Dehydrogenase (Quinone)
- Pancreatic Neoplasms
- Polymorphism, Genetic
- Quinone Reductases
- Risk Factors
- Superoxide Dismutase