Article
The vaccinia virus A18R DNA helicase is a postreplicative negative transcription elongation factor.
Journal of virology - 1 Sept 1998
Xiang Y, Simpson D A, Spiegel J, Zhou A, Silverman R H, Condit R C
Abstract excerpt
Loss of vaccinia virus A18R gene function results in an aberrant transcription profile termed promiscuous transcription, defined as transcription within regions of the genome which are normally transcriptionally silent late during infection. Promiscuous transcription results in an increase in the...
Topics
- Adenosine Triphosphatases
- Animals
- Cell Line
- Chlorocebus aethiops
- DNA Helicases
- DNA Replication
- Endoribonucleases
- Gene Expression Regulation, Viral
- Genes, Viral
- Mice
- Mice, Knockout
- Mutagenesis
- Peptide Elongation Factors
- Phenotype
- Polymerase Chain Reaction
- Vaccinia virus
- Virus Replication