Article
The dual-specificity phosphatase encoded by vaccinia virus, VH1, is essential for viral transcription in vivo and in vitro.
Journal of virology - 1 Dec 1995
Liu K, Lemon B, Traktman P
Abstract excerpt
The genetic complexity of vaccinia virus is such that as well as encoding its own transcription and replication machinery, it encodes two protein kinases and a protein phosphatase. The latter enzyme, designated VH1, is a prototype for the dual-specificity class of phosphatases. Here we report tha...
Topics
- Alleles
- Animals
- Base Sequence
- DNA Primers
- DNA Replication
- Dual-Specificity Phosphatases
- Gene Expression Regulation, Viral
- Isopropyl Thiogalactoside
- Kinetics
- L Cells
- Mice
- Molecular Sequence Data
- Phosphorylation
- Polymerase Chain Reaction
- Promoter Regions, Genetic
- Protein Tyrosine Phosphatases
- Recombinant Proteins
- Restriction Mapping