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Article

ORF18 Is a Transfactor That Is Essential for Late Gene Transcription of a Gammaherpesvirus

14 Sept 2006

Abstract excerpt

Lytic replication of the tumor-associated human gammaherpesviruses Epstein-Barr virus and Kaposi's sarcoma-associated herpesvirus has important implications in pathogenesis and tumorigenesis. Herpesvirus lytic genes have been temporally classified as exhibiting immediate-early (IE), early, and late expression kinetics. Though the regulation of IE and early gene expression has been studied extensively, very little...

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PMID: 16973577
DOI: 10.1128/jvi.00246-06

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ORF18 Is a Transfactor That Is Essential for Late Gene Transcription of a GammaherpesvirusPMID 16973577Read ↗

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