Article
A mutation in a purported regulatory gene affects control of sterol uptake in Saccharomyces cerevisiae.
Journal of bacteriology - 1 Aug 1998
Crowley J H, Leak F W, Shianna K V, Tove S, Parks L W
Abstract excerpt
Aerobically growing wild-type strains of Saccharomyces cerevisiae are unable to take exogenously supplied sterols from media. This aerobic sterol exclusion is vitiated under anaerobic conditions, in heme-deficient strains, and under some conditions of impaired sterol synthesis. Mutants which can take up sterols aerobically in heme-competent cells have been selected. One of these mutations, designated upc2-1,...
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