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Article

Cdc1 and the vacuole coordinately regulate Mn2+ homeostasis in the yeast Saccharomyces cerevisiae.

Genetics - 1 Apr 1998

Paidhungat M, Garrett S

Abstract excerpt

The yeast CDC1 gene encodes an essential protein that has been implicated in the regulation of cytosolic [Mn2+]. To identify factors that impinge upon Cdc1 or the Cdc1-dependent process, we isolated second-site suppressors of the conditional cdc1-1(Ts) growth defect. Recessive suppressors define 15 COS (CdcOne Suppressor) genes. Seven of the fifteen COS genes are required for biogenesis of the vacuole, an...

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Identifiers

PMID: 9560393
DOI: 10.1093/genetics/148.4.1787
PMCID: PMC1460059

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