Article
FEN2: a gene implicated in the catabolite repression-mediated regulation of ergosterol biosynthesis in yeast.
Yeast (Chichester, England) - 1 May 1996
Marcireau C, Joets J, Pousset D, Guilloton M, Karst F
Abstract excerpt
We have isolated and characterized a pleiotropic recessive mutation. fen2-1, that causes resistance to fenpropimorph and a low level of ergosterol in Saccharomyces cerevisiae. Ergosterol synthesis in the mutant strain was 5.5-fold slower than in the wild type; however, in vitro assays of the enzymes involved in ergosterol biosynthesis could not account for this low rate in the mutant. The mutant phenotype was...
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