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Article

Identification of thermodynamically relevant interactions between EF-Tu and backbone elements of tRNA.

Journal of molecular biology - 18 May 2001

Pleiss J A, Uhlenbeck O C

Abstract excerpt

A set of 45 different tRNAs, each containing a single deoxynucleotide substitution covering the upper half of the molecule was used in conjunction with a high-throughput ribonuclease protection assay to investigate the thermodynamic role of 2' hydroxyl groups in stabilizing a complex with elongation factor Tu (EF-Tu) from Thermus thermophilus. Five distinct 2' hydroxyl groups were identified where substitution...

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Identifiers

PMID: 11352580
DOI: 10.1006/jmbi.2001.4612

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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