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Article

Longitudinal analysis of circulating myeloma cells detected by allele specific mRNA in situ hybridization.

American journal of hematology - 1 Aug 1998

Brown R D, Luo X F, Gibson J, Brisco M, Sykes P, Morley A, Joshua D

Abstract excerpt

Individual myeloma cells in the peripheral blood of 7 patients with multiple myeloma were detected by mRNA in situ hybridization (ISH) using biotinylated antisense oligonucleotide probes to non-germline sequences of the CDR3 region of the immunoglobulin heavy chain gene. Peripheral blood samples...

Topics

Adult
Aged
Aged, 80 and over
Alleles
Antisense Elements (Genetics)
Clone Cells
Disease Progression
Female
Humans
In Situ Hybridization
Longitudinal Studies
Male

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Multiple Myeloma

Plasma Cells

RNA, Messenger

Source

Identifiers

PMID: 9692389
DOI: 10.1002/(sici)1096-8652(199808)58:4<273::aid-ajh4>3.0.co;2-n

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9692389-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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