Article
Detection and quantitation of malignant cells in the peripheral blood of multiple myeloma patients.
Blood - 1 Oct 1992
Billadeau D, Quam L, Thomas W, Kay N, Greipp P, Kyle R, Oken M M, Van Ness B
Abstract excerpt
One of the distinguishing features of multiple myeloma (MM) is the proliferation of plasma cells that home to the bone marrow (BM). However, there still remains some uncertainty concerning the presence of related malignant cells in the peripheral blood of myeloma patients. Using consensus oligonucleotide primers, we amplified the third complementary determining region (CDR3) of rearranged immunoglobulin heavy...
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