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Article

The involvement of the fibronectin type II-like modules of human gelatinase A in cell surface localization and activation.

The Journal of biological chemistry - 7 Aug 1998

Steffensen B, Bigg H F, Overall C M

Abstract excerpt

Recombinant collagen-binding domain (rCBD) comprising the three fibronectin type II-like modules of human gelatinase A was found to compete the zymogen form of this matrix metalloproteinase from the cell surface of normal human fibroblasts in culture. Upon concanavalin A treatment of cells, the induced cellular activation of gelatinase A was markedly elevated in the presence of the rCBD. Therefore, the...

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Source

Identifiers

PMID: 9685420
DOI: 10.1074/jbc.273.32.20622

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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