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Article

Evidence for dinucleotide flipping by DNA photolyase.

The Journal of biological chemistry - 7 Aug 1998

Vande Berg B J, Sancar G B

Abstract excerpt

DNA photolyases repair pyrimidine dimers via a reaction in which light energy drives electron donation from a catalytic chromophore, FADH-, to the dimer. The crystal structure of Escherichia coli photolyase suggested that the pyrimidine dimer is flipped out of the DNA helix and into a cavity that leads from the surface of the enzyme to FADH-. We have tested this model using the Saccharomyces cerevisiae Phr1...

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Identifiers

PMID: 9685377
DOI: 10.1074/jbc.273.32.20276

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Evidence for dinucleotide flipping by DNA photolyase.PMID 9685377Read ↗

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Crystal Structures of Bacterial (6-4) Photolyase Mutants with Impaired DNA Repair Activity.Semantic proximity Read ↗

Dissection of functional domains in Escherichia coli DNA photolyase by linker-insertion mutagenesis.Semantic proximity Read ↗

Synergistic modulation of cyclobutane pyrimidine dimer photoproduct formation and deamination at a TmCG site over a full helical DNA turn in a nucleosome core particle.Semantic proximity Read ↗

Light-induced reactions of Escherichia coli DNA photolyase monitored by Fourier transform infrared spectroscopy.Semantic proximity Read ↗

Active site of Escherichia coli DNA photolyase: mutations at Trp277 alter the selectivity of the enzyme without affecting the quantum yield of photorepair.Semantic proximity Read ↗

Investigation of the cyclobutane pyrimidine dimer (CPD) photolyase DNA recognition mechanism by NMR analyses.Semantic proximity Read ↗

The molecular origin of high DNA-repair efficiency by photolyase.Semantic proximity Read ↗

Chromatin structure modulates DNA repair by photolyase in vivo.Semantic proximity Read ↗

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