Article
Periconceptional multivitamin intake during early pregnancy, genetic variation of acetyl-N-transferase 1 (NAT1), and risk for orofacial clefts.
Birth defects research. Part A, Clinical and molecular teratology - 1 Nov 2004
Lammer Edward J, Shaw Gary M, Iovannisci David M, Finnell Richard H
Abstract excerpt
BACKGROUND: Periconceptional supplementation of multivitamins that include folic acid have been shown to prevent several birth defects, including neural tube defects and orofacial clefts. We investigated whether polymorphic variants of fetal acetyl-N-transferase 1 (NAT1), an enzyme involved in th...
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