Combined effect of polymorphic GST genes on individual susceptibility to lung cancer.

doi:10.1002/(sici)1097-0215(19980812)77:4<516::aid-ijc7>3.0.co;2-x

Article

Combined effect of polymorphic GST genes on individual susceptibility to lung cancer.

International journal of cancer - 12 Aug 1998

Saarikoski S T, Voho A, Reinikainen M, Anttila S, Karjalainen A, Malaveille C, Vainio H, Husgafvel-Pursiainen K, Hirvonen A

Abstract excerpt

Glutathione S-transferases (GSTs) are known to take part in detoxification of many potentially carcinogenic compounds. Therefore, polymorphisms of the GST genes have been considered as potentially important modifiers of individual risk of environmentally induced cancers. The association between l...

Topics

Adenocarcinoma
Carcinoma, Squamous Cell
Disease Susceptibility
Female
Genotype
Glutathione Transferase
Humans
Lung Neoplasms
Male
Polymorphism, Genetic

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.