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Article

Combined effect of polymorphic GST genes on individual susceptibility to lung cancer.

International journal of cancer - 12 Aug 1998

Saarikoski S T, Voho A, Reinikainen M, Anttila S, Karjalainen A, Malaveille C, Vainio H, Husgafvel-Pursiainen K, Hirvonen A

Abstract excerpt

Glutathione S-transferases (GSTs) are known to take part in detoxification of many potentially carcinogenic compounds. Therefore, polymorphisms of the GST genes have been considered as potentially important modifiers of individual risk of environmentally induced cancers. The association between lack of glutathione S-transferase M1 gene (GSTM1 null genotype) and susceptibility to smoking-related lung cancer has...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 9679751
DOI: 10.1002/(sici)1097-0215(19980812)77:4<516::aid-ijc7>3.0.co;2-x

Genes

GSTM1
GSTT1
GSTM3
GSTP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Combined effect of polymorphic GST genes on individual susceptibility to lung cancer.PMID 9679751Read ↗

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Glutathione S-transferase T1 null-genotype is associated with an increased risk of lung cancer.Semantic proximity Read ↗

The GSTM1 null genotype as a potential risk modifier for squamous cell carcinoma of the lung.Semantic proximity Read ↗

Meta- and pooled analysis of GSTT1 and lung cancer: a HuGE-GSEC review.Semantic proximity Read ↗

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Glutathione S-transferase M1 (GSTM1) polymorphisms and lung cancer: a literature-based systematic HuGE review and meta-analysis.Semantic proximity Read ↗

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Combined effects of glutathione S-transferase M1 and T1 polymorphisms on risk of lung cancer: Evidence from a meta-analysis.Semantic proximity Read ↗

Combined genetic polymorphism and risk for development of lung cancer.Semantic proximity Read ↗

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