Article
Combined effect of GSTM1, GSTT1 and GSTP1 polymorphisms on histological subtypes of lung cancer.
Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals - 1 May 2008
Sobti R C, Kaur Pushpinder, Kaur Satinder, Janmeja A K, Jindal S K, Kishan J, Raimondi Sara
Abstract excerpt
Genetic polymorphisms are natural genetic variations in the gene sequence that occur at a frequency of >1% in the population. This genetic variability (polymorphisms) can be a factor in cancer risk. The functional polymorphisms in GST genes play an important role in susceptibility to lung cancer. In our previous study, we reported that the combination of certain genotypes of GSTM1, GSTT1 and CYP1A1 is associated...
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