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Article

Glutathione S-transferase T1 null-genotype is associated with an increased risk of lung cancer.

International journal of cancer - 10 Jun 2004

Sørensen Mette, Autrup Herman, Tjønneland Anne, Overvad Kim, Raaschou-Nielsen Ole

Abstract excerpt

Glutathione S-transferases (GSTs) are involved in detoxification of carcinogens, e.g., from tobacco smoke. Therefore, polymorphisms in the GST genes have been considered as potential modifiers of individual cancer risk. In a population-based case-cohort study where cases and the subcohort sample were matched on duration of smoking, we investigated the occurrence of lung cancer and histological subtypes of lung...

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Source

Identifiers

PMID: 15069685
DOI: 10.1002/ijc.20075

Genes

GSTT1
GSTP1
GSTM1
GSTM3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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