Article
Glutathione S-transferase T1 null-genotype is associated with an increased risk of lung cancer.
International journal of cancer - 10 Jun 2004
Sørensen Mette, Autrup Herman, Tjønneland Anne, Overvad Kim, Raaschou-Nielsen Ole
Abstract excerpt
Glutathione S-transferases (GSTs) are involved in detoxification of carcinogens, e.g., from tobacco smoke. Therefore, polymorphisms in the GST genes have been considered as potential modifiers of individual cancer risk. In a population-based case-cohort study where cases and the subcohort sample...
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