Meta- and pooled analyses of the effects of glutathione S-transferase M1 polymorphisms and smoking on lung cancer risk.

doi:10.1093/carcin/23.8.1343

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Article

Meta- and pooled analyses of the effects of glutathione S-transferase M1 polymorphisms and smoking on lung cancer risk.

Carcinogenesis - 1 Aug 2002

Benhamou Simone, Lee Won Jin, Alexandrie Anna-Karin, Boffetta Paolo, Bouchardy Christine, Butkiewicz Dorota, Brockmöller Jurgen, Clapper Margie L, Daly Ann, Dolzan Vita, Ford Jean, Gaspari Laura, Haugen Aage, Hirvonen Ari, Husgafvel-Pursiainen Kirsti, Ingelman-Sundberg Magnus, Kalina Ivan, Kihara Masahiro, Kremers Pierre, Le Marchand Loïc, London Stephanie J, Nazar-Stewart Valle, Onon-Kihara Masako, Rannug Agneta, Romkes Marjorie, Ryberg David, Seidegard Janeric, Shields Peter, Strange Richard C, Stücker Isabelle, To-Figueras Jordi, Brennan Paul, Taioli Emanuela

Abstract excerpt

Susceptibility to lung cancer may in part be attributable to inter-individual variability in metabolic activation or detoxification of tobacco carcinogens. The glutathione S-transferase M1 (GSTM1) genetic polymorphism has been extensively studied in this context; two recent meta-analyses of case-control studies suggested an association between GSTM1 deletion and lung cancer. At least 15 studies have been...

Topics

Case-Control Studies
Cocarcinogenesis
Genetic Predisposition to Disease
Glutathione Transferase
Humans
Lung Neoplasms
Polymorphism, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Smoking

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Open in PubMed

Identifiers

PMID: 12151353
DOI: 10.1093/carcin/23.8.1343

Genes

GSTM1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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