Article
Genetic polymorphisms of glutathione S-transferases as modulators of lung cancer susceptibility.
Carcinogenesis - 1 Sept 2002
Stücker Isabelle, Hirvonen Ari, de Waziers Isabelle, Cabelguenne Arnauld, Mitrunen Katja, Cénée Sylvie, Koum-Besson Elisabeth, Hémon Denis, Beaune Philippe, Loriot Marie-Anne
Abstract excerpt
Some of the glutathione S-transferases (GSTs) are polymorphic and may play a role in lung cancer susceptibility. Our previous study in a French Caucasian study population suggested GSTM1 null genotype as a moderate risk factor for lung cancer. Here we extended the study to investigate the potential role of GSTT1 and GSTP1 polymorphisms in susceptibility to lung cancer, either separately or in combination. The...
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