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Article

Possible risk modification by CYP1A1, GSTM1 and GSTT1 gene polymorphisms in lung cancer susceptibility in a South Indian population.

Journal of human genetics - 1 Jan 2005

Sreeja Leelakumari, Syamala Vani, Hariharan Sreedharan, Madhavan Jayaprakash, Devan Sivanandan Choondal, Ankathil Ravindran

Abstract excerpt

Susceptibility to lung cancer has been shown to be modulated by inheritance of polymorphic genes encoding cytochrome P450 1A1 (CYP1A1) and glutathione S transferases (GSTM1 and GSTT1), which are involved in the bioactivation and detoxification of environmental toxins. As the incidence of lung cancer is known to differ according to ethnicity, we have conducted a case-control study of 146 South Indian lung cancer...

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Source

Identifiers

PMID: 16228113
DOI: 10.1007/s10038-005-0303-3

Genes

GSTT1
GSTM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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