Article
Lack of association of Graves' disease with the A2 allele of the interleukin-1 receptor antagonist gene in a white European population.
European journal of endocrinology - 1 Jun 1998
Mühlberg T, Kirchberger M, Spitzweg C, Herrmann F, Heberling H J, Heufelder A E
Abstract excerpt
OBJECTIVE: To assess whether the A2-type IL-1RA polymorphism is associated with Graves' disease and Graves' ophthalmopathy. Several reports have described a genetic association between the A2 allele of the interleukin-1 receptor antagonist (IL-1RA) gene and certain inflammatory and autoimmune dis...
Topics
- Alleles
- Case-Control Studies
- Chromosome Mapping
- Female
- Genetic Carrier Screening
- Genetic Predisposition to Disease
- Germany
- Graves Disease
- Humans
- Interleukin 1 Receptor Antagonist Protein
- Male
- Polymorphism, Genetic
- Receptors, Interleukin-1
- Sialoglycoproteins
- White People
