Article
T cell receptor beta chain gene polymorphisms in Graves' disease.
Acta endocrinologica - 1 Jun 1993
Pickerill A P, Watson P F, Tandon N, Weetman A P
Abstract excerpt
Graves' disease, or subgroups of such patients with thyroglobulin antibodies or HLA-DR3, have been associated with a restriction fragment length polymorphism of the T cell receptor beta chain constant region gene but not all studies are in agreement. We have examined 58 patients with Graves' dise...
Topics
- Alleles
- Antibody Formation
- Autoantibodies
- Chi-Square Distribution
- DNA Probes
- Gene Frequency
- Genetic Predisposition to Disease
- Genotype
- Graves Disease
- HLA-DR3 Antigen
- Humans
- Polymorphism, Restriction Fragment Length
