Analysis of HIV-1 Tat effects in Xenopus laevis embryos.

doi:10.1007/BF02253471

Back to search

Article

Analysis of HIV-1 Tat effects in Xenopus laevis embryos.

Journal of biomedical science - 1 Jan 1998

Venanzi S, Destrée O H, Gigliani F, Battaglia P A

Abstract excerpt

Tat is one of the regulatory proteins of the HIV-1 virus. To date, besides the transactivation activity, a myriad of effects exerted by HIV-1 Tat on cellular and viral genes have been observed. The present study investigated the in vivo effects of HIV-1 Tat protein in the Xenopus embryo. We adopt...

Topics

Animals
Cell Nucleus
Cytoplasm
Down-Regulation
Embryo, Nonmammalian
Gene Expression Regulation, Developmental
Gene Products, tat
Mutation
Peptide Fragments
Phenotype
RNA, Messenger
Transfection
Xenopus laevis
tat Gene Products, Human Immunodeficiency Virus

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.