Article
Analysis of HIV-1 Tat effects in Xenopus laevis embryos.
Journal of biomedical science - 1 Jan 1998
Venanzi S, Destrée O H, Gigliani F, Battaglia P A
Abstract excerpt
Tat is one of the regulatory proteins of the HIV-1 virus. To date, besides the transactivation activity, a myriad of effects exerted by HIV-1 Tat on cellular and viral genes have been observed. The present study investigated the in vivo effects of HIV-1 Tat protein in the Xenopus embryo. We adopted the Xenopus system since expression of putative regulatory factors in the embryo has been widely used as a quick and...
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