Article
Overexpression of a cellular retinoic acid binding protein (xCRABP) causes anteroposterior defects in developing Xenopus embryos.
Development (Cambridge, England) - 1 Apr 1994
Dekker E J, Vaessen M J, van den Berg C, Timmermans A, Godsave S, Holling T, Nieuwkoop P, Geurts van Kessel A, Durston A
Abstract excerpt
We have isolated the first Xenopus laevis cDNA coding for a cellular retinoic acid binding protein (xCRABP). xCRABP contains a single open reading frame, coding for an approximately 15 x 10(3) M(r) protein. Northern blot analysis shows that this cDNA hybridizes to a mRNA that is expressed both ma...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Blotting, Northern
- Cloning, Molecular
- Gene Expression
- In Situ Hybridization
- Microinjections
- Molecular Sequence Data
- Morphogenesis
- Phenotype
- Receptors, Retinoic Acid
- Xenopus laevis