Article
Beta-catenin/Tcf-regulated transcription prior to the midblastula transition.
Development (Cambridge, England) - 1 Dec 2002
Yang Jing, Tan Change, Darken Rachel S, Wilson Paul A, Klein Peter S
Abstract excerpt
Following fertilization, the zygotic genome in many organisms is quiescent until the midblastula transition (MBT), when large-scale transcription begins. In Xenopus embryos, for example, transcription is believed to be repressed until the twelfth cell division. Thus, although dorsal-ventral patterning begins during the first cell cycle, little attention has been given to transcriptional regulation in pre-MBT...
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