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Article

Stimulation of the XPB ATP-dependent helicase by the beta subunit of TFIIE.

Nucleic acids research - 1 Jan 2005

Lin Yin C, Gralla Jay D

Abstract excerpt

TFIIE and TFIIH are essential for the promoter opening and escape that occurs as RNA polymerase II transits into early elongation. XPB, a subunit of TFIIH, contains an ATP-dependent helicase activity that is used in both of these processes. Here, we show that the smaller beta subunit of TFIIE stimulates the XPB helicase and ATPase activities. The larger alpha subunit can use its known inhibitory activity to...

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Identifiers

PMID: 15917439
DOI: 10.1093/nar/gki623
PMCID: PMC1140373

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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