The Ah receptor is not involved in 2,3,7,8-tetrachlorodibenzo- p-dioxin-mediated apoptosis in human leukemic T cell lines.

doi:10.1074/jbc.273.31.19853

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Article

The Ah receptor is not involved in 2,3,7,8-tetrachlorodibenzo- p-dioxin-mediated apoptosis in human leukemic T cell lines.

The Journal of biological chemistry - 31 Jul 1998

Hossain A, Tsuchiya S, Minegishi M, Osada M, Ikawa S, Tezuka F A, Kaji M, Konno T, Watanabe M, Kikuchi H

Abstract excerpt

2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) is a common environmental pollutant causing public concern. Its toxic effects include disruption of the immune, endocrine, and reproductive systems, impairment of fetal development, carcinogenicity, and lethality in rodents. Here, we report that TCDD ind...

Topics

Apoptosis
Aspartic Acid
Benzofurans
Calcium-Calmodulin-Dependent Protein Kinases
Cycloheximide
DNA Fragmentation
Environmental Pollutants
Enzyme Activation
Gene Expression Regulation, Neoplastic
Genistein
Humans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

JNK Mitogen-Activated Protein Kinases

Lymphoma, T-Cell

Microscopy, Fluorescence

Mitogen-Activated Protein Kinases

Mutation

Polychlorinated Dibenzodioxins

Proto-Oncogene Proteins c-bcl-2

Source

Open in PubMed

Identifiers

PMID: 9677421
DOI: 10.1074/jbc.273.31.19853

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9677421-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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The Ah receptor is not involved in 2,3,7,8-tetrachlorodibenzo- p-dioxin-mediated apoptosis in human leukemic T cell lines.PMID 9677421Read ↗

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