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Article

Divergent Effects of Dioxin- or Non-Dioxin-Like Polychlorinated Biphenyls on the Apoptosis of Primary Cell Culture from the Mouse Pituitary Gland.

PloS one - 1 Jan 2016

Raggi Francesco, Russo Dania, Urbani Claudio, Sardella Chiara, Manetti Luca, Cappellani Daniele, Lupi Isabella, Tomisti Luca, Martino Enio, Marcocci Claudio, Bogazzi Fausto

Abstract excerpt

Polychlorinated biphenyls (PCBs) can disrupt the endocrine function, promote neoplasms and regulate apoptosis in some tissues; however, it is unknown whether PCBs can affect the apoptosis of pituitary cells. The study evaluated the effect of PCBs on the apoptosis of normal pituitary cells and the underlying mechanisms. Primary cell cultures obtained from mouse pituitary glands were exposed to Aroclor 1254 or...

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PMID: 26752525
DOI: 10.1371/journal.pone.0146729
PMCID: PMC4709048

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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