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Article

Functional analysis of six human aryl hydrocarbon receptor variants in human breast cancer and mouse hepatoma cell lines.

Toxicology - 9 Nov 2010

Celius Trine, Matthews Jason

Abstract excerpt

The aryl hydrocarbon receptor (AHR) is a ligand-dependent transcription factor that mediates the toxic responses of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). The identification and functional analysis of AHR single nucleotide polymorphisms is important in understanding the functional diversity of this receptor as it might give rise to individuals with differing sensitivities to TCDD. In this study, the...

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Share to Carcinoma, Hepatocellular
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Source

Identifiers

PMID: 20817071
DOI: 10.1016/j.tox.2010.08.015

Genes

AHR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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