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Article

Differential effects of cisplatin and MNNG on dna mutants of Escherichia coli.

Mutation research - 15 Oct 2005

Calmann Melissa A, Marinus M G

Abstract excerpt

DNA mismatch repair (MMR) in mammalian cells or Escherichia coli dam mutants increases the cytotoxic effects of cisplatin and N-methyl-N'-nitro-N-nitrosoguanidine (MNNG). We found that, unlike wildtype, the dnaE486 (alpha catalytic subunit of DNA polymerase III holoenzyme) mutant, and a DnaX (cla...

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Identifiers

PMID: 16144703
DOI: 10.1016/j.mrfmmm.2005.06.030
PMCID: PMC2927670

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16144703-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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