Article
Locus controlling LDL cholesterol response to dietary cholesterol is on baboon homologue of human chromosome 6.
Arteriosclerosis, thrombosis, and vascular biology - 1 Oct 2002
Kammerer Candace M, Rainwater David L, Cox Laura A, Schneider Jennifer L, Mahaney Michael C, Rogers Jeffrey, VandeBerg John L
Abstract excerpt
OBJECTIVE: Cholesterolemic responses to dietary lipids are known to be heritable, but the genes that may affect this response have yet to be identified. Using segregation analysis, we previously detected a potential quantitative trait locus (QTL) in baboons that influenced low density lipoprotein cholesterol response to dietary cholesterol. We performed linkage analyses to locate this QTL by using data on the...
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