Evidence that multiple genes influence baseline concentrations and diet response of Lp(a) in baboons.

doi:10.1161/01.atv.19.11.2696

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Article

Evidence that multiple genes influence baseline concentrations and diet response of Lp(a) in baboons.

Arteriosclerosis, thrombosis, and vascular biology - 1 Nov 1999

Rainwater D L, Kammerer C M, VandeBerg J L

Abstract excerpt

We investigated the response of lipoprotein(a) [Lp(a)] levels to dietary fat and cholesterol in 633 baboons fed a series of 3 diets: a basal diet low in cholesterol and fat, a high-fat diet, and a diet high in fat and cholesterol. Measurement of serum concentrations in samples taken while the baboons were sequentially fed the 3 diets allowed us to analyze 3 Lp(a) variables: Lp(a)(Basal), Lp(a)(RF) (response to...

Topics

Animals
Cholesterol, Dietary
Cholesterol, LDL
Female
Gene Expression
Genetic Variation
Genotype
Lipoprotein(a)
Male
Papio
Phenotype

Source

Open in PubMed

Identifiers

PMID: 10559013
DOI: 10.1161/01.atv.19.11.2696

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