Article
Cloning and characterization of a GC-box binding protein, G10BP-1, responsible for repression of the rat fibronectin gene.
Molecular and cellular biology - 1 Aug 1998
Oda E, Shirasuna K, Suzuki M, Nakano K, Nakajima T, Oda K
Abstract excerpt
Fibronectin (FN) is an extracellular matrix protein that connects the extracellular matrix to intracellular cortical actin filaments through binding to its cell surface receptor, alpha5beta1, a member of the integrin superfamily. The expression level of FN is reduced in most tumor cells, facilitating their anchorage-independent growth by still unclarified mechanisms. The cDNA clone encoding G-rich sequence...
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