Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Transcriptional regulation of vascular endothelial growth factor C by oxidative and thermal stress is mediated by lens epithelium-derived growth factor/p75.

Neoplasia (New York, N.Y.) - 1 Sept 2009

Cohen Batya, Addadi Yoseph, Sapoznik Stav, Meir Gila, Kalchenko Vyacheslav, Harmelin Alon, Ben-Dor Shifra, Neeman Michal

Abstract excerpt

Vascular endothelial growth factor C (VEGF-C) plays a critical role in tumor lymphangiogenesis and lymph node metastasis. We report here that VEGF-C expression is regulated by microenvironmental stress including hyperthermia and oxidative stress. Furthermore, we show that this stress response is...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromatin Immunoprecipitation
Share to Glioma
Share to Immunoblotting

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to In Situ Hybridization

Share to Intercellular Signaling Peptides and Proteins

Share to Luciferases

Share to Response Elements

Share to Vascular Endothelial Growth Factor C

Source

Open in PubMed Open full text

Identifiers

PMID: 19724686
DOI: 10.1593/neo.09636
PMCID: PMC2735804

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19724686-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Transcriptional regulation of vascular endothelial growth factor C by oxidative and thermal stress is mediated by lens epithelium-derived growth factor/p75.PMID 19724686Read ↗

Expression of the Stress Response Oncoprotein LEDGF/p75 in Human Cancer: A Study of 21 Tumor TypesSemantic proximity Read ↗

The Emerging Roles of the Stress Epigenetic Reader LEDGF/p75 in Cancer Biology and Therapy Resistance: Mechanisms and Targeting OpportunitiesSemantic proximity Read ↗

Human MCS5A1 candidate breast cancer susceptibility gene FBXO10 is induced by cellular stress and correlated with lens epithelium-derived growth factor (LEDGF).Semantic proximity Read ↗

LEDGF/p75 is Required for an Efficient DNA Damage ResponseSemantic proximity Read ↗

Regulation of heavy subunit chain of gamma-glutamylcysteine synthetase by tumor necrosis factor-alpha in lens epithelial cells: role of LEDGF/p75.Semantic proximity Read ↗

DNA binding domains and nuclear localization signal of LEDGF: contribution of two helix-turn-helix (HTH)-like domains and a stretch of 58 amino acids of the N-terminal to the trans-activation potential of LEDGF.Semantic proximity Read ↗

Oncogenic Human Papillomaviruses Activate the Tumor-Associated Lens Epithelial-Derived Growth Factor (LEDGF) GeneSemantic proximity Read ↗

DNA methylation as an epigenetic mechanism in the regulation of LEDGF expression and biological response in aging and oxidative stressSemantic proximity Read ↗

Dysfunction of the stress-responsive FOXC1 transcription factor contributes to the earlier-onset glaucoma observed in Axenfeld-Rieger syndrome patients.Semantic proximity Read ↗

The TG-interacting factor TGIF1 regulates stress-induced proinflammatory phenotype of endothelial cells.Semantic proximity Read ↗

Cloning and characterization of a GC-box binding protein, G10BP-1, responsible for repression of the rat fibronectin gene.Semantic proximity Read ↗

The stress-responsive gene GADD45G is a functional tumor suppressor, with its response to environmental stresses frequently disrupted epigenetically in multiple tumors.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.