Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Transcription factor Sp1 regulates basal transcription of the human DRG2 gene.

Biochimica et biophysica acta - 1 Mar 2011

Kim Hyo Jeong, Ko Myoung Seok, Kim Hong Kyung, Cho Wha Ja, Lee Seon Ho, Lee Byung Ju, Park Jeong Woo

Abstract excerpt

Developmentally regulated GTP-binding protein 2 (DRG2) is an evolutionarily conserved GTP-binding protein. DRG2 mRNA expression has been confirmed in many animal and human tissues. DRG2 is thought to play an essential role in the control of cell growth and differentiation. However, transcriptional regulation of DRG2 is largely unknown. To investigate the mechanisms controlling DRG2 expression, we cloned 1509bp of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Binding Sites
Share to Cell Survival
Share to Gene Silencing

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to GTP-Binding Proteins

Share to K562 Cells

Share to Sequence Deletion

Share to Sp1 Transcription Factor

Share to Transcription, Genetic

Source

Identifiers

PMID: 21296692
DOI: 10.1016/j.bbagrm.2011.01.004

Genes

DRG2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Transcription factor Sp1 regulates basal transcription of the human DRG2 gene.PMID 21296692Read ↗

Functional interaction of CP2 with GATA-1 in the regulation of erythroid promoters.Semantic proximity Read ↗

CP2 binding to the promoter is essential for the enhanced transcription of globin genes in erythroid cells.Semantic proximity Read ↗

Human differentiation-related gene NDRG1 is a Myc downstream-regulated gene that is repressed by Myc on the core promoter regionSemantic proximity Read ↗

A naturally occurring gamma globin gene mutation enhances SP1 binding activity.Semantic proximity Read ↗

Far Upstream Element Binding Protein Plays a Crucial Role in Embryonic Development, Hematopoiesis, and Stabilizing Myc Expression LevelsSemantic proximity Read ↗

Transcription factors Krüppel-like factor 4 and paired box 5 regulate the expression of the Grainyhead-like genes.Semantic proximity Read ↗

Upstream stimulatory factors are involved in the P1 promoter directed transcription of the A beta H-J-J locus.Semantic proximity Read ↗

Characterization of a GC-rich region containing Sp1 binding site(s) as a constitutive responsive element of the alpha 2(I) collagen gene in human fibroblasts.Semantic proximity Read ↗

GCF2: expression and molecular analysis of repression.Semantic proximity Read ↗

TTF-1 response element is critical for temporal and spatial regulation and necessary for hormonal regulation of human surfactant protein-A2 promoter activity.Semantic proximity Read ↗

Overexpression of DRG2 Increases G2/M Phase Cells and Decreases Sensitivity to Nocodazole-Induced ApoptosisSemantic proximity Read ↗

Molecular and functional characterization of the murine ldh2 promoter region: Sp-binding GC-box domains are the key cis-elements regulating ldh2 gene expression during spermatogenesis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.