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Overexpression of FRA1 (FOSL1) Leads to Global Transcriptional Perturbations, Reduced Cellular Adhesion and Altered Cell Cycle Progression

24 Sept 2023

Abstract excerpt

superfamily. FRA1 is expressed in most tissues at low levels, and its expression is robustly induced in response to extracellular signals, leading to downstream cellular processes. However, abnormal FRA1 overexpression has been reported in various pathological states, including tumor progression and inflammation. To date, the molecular effects of FRA1 overexpression are still not understood. Therefore, the aim of...

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Cell Adhesion Molecules Research
Cellular transport and secretion
Phagocytosis and Immune Regulation

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 37830558
DOI: 10.3390/cells12192344

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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