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Article

Determinants for transformation induced by the Axl receptor tyrosine kinase.

Oncogene - 18 Jun 1998

Burchert A, Attar E C, McCloskey P, Fridell Y W, Liu E T

Abstract excerpt

The Axl receptor tyrosine kinase is a transforming oncogene in NIH3T3 cells. In order to define structural requirements of the Axl receptor necessary for transformation we passaged recombinant retroviruses carrying the axl cDNA in NIH3T3 cells, generating randomly mutated axl variants. Using this strategy, we have isolated three axl viral strains (1B1, SV8, and FFa4) that show augmented 3T3 cell transforming...

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Identifiers

PMID: 9671397
DOI: 10.1038/sj.onc.1201865

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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