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Article

Allelic loss of chromosome 10q23 is associated with tumor progression in breast carcinomas.

Oncogene - 9 Jul 1998

Bose S, Wang S I, Terry M B, Hibshoosh H, Parsons R

Abstract excerpt

To determine the status of chromosome 10q23 in primary breast carcinomas, in situ and invasive carcinomas were analysed for allelic loss using microsatellite markers spanning the 10q23 region. No LOH was seen in pure intraductal carcinomas (0/20 cases). On the other hand, LOH was observed in 40% (17/42) of invasive carcinomas (P = 0.0005). Interestingly, in situ lesions found in invasive tumors displayed LOH....

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Source

Identifiers

PMID: 9671321
DOI: 10.1038/sj.onc.1201940

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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