Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Allelic loss of chromosome 10q23 is associated with tumor progression in breast carcinomas.

Oncogene - 9 Jul 1998

Bose S, Wang S I, Terry M B, Hibshoosh H, Parsons R

Abstract excerpt

To determine the status of chromosome 10q23 in primary breast carcinomas, in situ and invasive carcinomas were analysed for allelic loss using microsatellite markers spanning the 10q23 region. No LOH was seen in pure intraductal carcinomas (0/20 cases). On the other hand, LOH was observed in 40%...

Topics

Breast Neoplasms
Carcinoma in Situ
Carcinoma, Ductal, Breast
Chromosomes, Human, Pair 10
Disease Progression
Female
Humans
Loss of Heterozygosity
Mutation
Neoplasm Invasiveness
PTEN Phosphohydrolase
Phosphoric Monoester Hydrolases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Protein Tyrosine Phosphatases

Tumor Suppressor Proteins

Source

Identifiers

PMID: 9671321
DOI: 10.1038/sj.onc.1201940

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9671321-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Allelic loss of chromosome 10q23 is associated with tumor progression in breast carcinomas.PMID 9671321Read ↗

Correlation of allelic losses and clinicopathological factors in 504 primary breast cancers.Semantic proximity Read ↗

Allelic loss on chromosome 10 in prostate adenocarcinoma.Semantic proximity Read ↗

Allelic loss of the PTEN region (10q23) in breast carcinomas of poor pathophenotypeSemantic proximity Read ↗

Allelic loss on chromosome 9q is associated with lymph node metastasis of primary breast cancer.Semantic proximity Read ↗

Allelic loss on chromosome 1p is Associated with progression and lymph node metastasis of primary breast carcinomaSemantic proximity Read ↗

Genomic alterations in human breast carcinomas.Semantic proximity Read ↗

Association of 8p23 deletions with poor survival in head and neck cancer.Semantic proximity Read ↗

Detailed deletion analysis of sporadic breast tumors defines an interstitial region of allelic loss on 17q25.Semantic proximity Read ↗

Comparative allelotype of in situ and invasive human breast cancer: high frequency of microsatellite instability in lobular breast carcinomas.Semantic proximity Read ↗

Loss of heterozygosity on chromosome 11 q in breast cancer.Semantic proximity Read ↗

Allelic losses at loci on chromosome 10 are associated with metastasis and progression of human prostate cancer.Semantic proximity Read ↗

Chromosome 10 allelic loss in malignant melanoma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.