Article
K-ras oncogene mutations indicate malignancy in cystic tumors of the pancreas.
Annals of surgery - 1 Jul 1998
Bartsch D, Bastian D, Barth P, Schudy A, Nies C, Kisker O, Wagner H J, Rothmund M
Abstract excerpt
OBJECTIVE: To evaluate clinical parameters, presurgical diagnostic tests, histologic findings, and the presence of K-ras oncogene mutations in cystic tumors of the pancreas to determine which best predict malignancy. SUMMARY BACKGROUND DATA: Because presurgical, intraoperative, and final patholog...
Topics
- Adult
- Aged
- Cholangiopancreatography, Endoscopic Retrograde
- DNA Mutational Analysis
- DNA, Neoplasm
- Female
- Genes, ras
- Humans
- Male
- Middle Aged
- Mutation
- Neoplasms, Cystic, Mucinous, and Serous
- Pancreatic Neoplasms
- Polymerase Chain Reaction
- Prognosis
- Retrospective Studies