Article
Diagnostic utility of K-ras mutations in fine-needle aspirates of pancreatic masses.
Gastroenterology - 1 May 1996
Villanueva A, Reyes G, Cuatrecasas M, Martínez A, Erill N, Lerma E, Farré A, Lluís F, Capellá G
Abstract excerpt
BACKGROUND & AIMS: Mutations at codon 12 of the K-ras gene are present in 65%-100% of carcinomas of human exocrine pancreas and could be used as a potential tumor marker at the tissue level. The purpose of this study was to assess, in large series of patients, the utility of K-ras mutation analysis to evaluate fine-needle aspirates of pancreatic masses. METHODS: One hundred fifteen fine-needle aspirates obtained...
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