Article
Kras mutation analysis of fine needle aspirate under EUS guidance facilitates risk stratification of patients with pancreatic mass.
Journal of clinical gastroenterology - 1 Jan 2000
Maluf-Filho Fauze, Kumar Atul, Gerhardt René, Kubrusly Márcia, Sakai Paulo, Hondo Fabio, Matuguma Sergio Eiji, Artifon Everson, Monteiro da Cunha José Eduardo, César Machado Marcel Cerqueira, Ishioka Shinichi, Forero Elias
Abstract excerpt
OBJECTIVES: The accuracy of endoscopic ultrasound-fine needle aspiration cytology (EUS-FNAC) for the diagnosis of pancreatic cancer is suboptimal. Mutational activation of the kras oncogene is almost universally present in pancreatic cancer tissue. We, therefore, investigated if analysis for mutant kras gene in the EUS-FNAC aspirates supplements cytopathology for the diagnosis of pancreatic adenocarcinoma (PAC)....
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