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Article

Preoperative GNAS and KRAS testing in the diagnosis of pancreatic mucinous cysts.

Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Aug 2014

Singhi Aatur D, Nikiforova Marina N, Fasanella Kenneth E, McGrath Kevin M, Pai Reetesh K, Ohori N Paul, Bartholow Tanner L, Brand Randall E, Chennat Jennifer S, Lu Xuong, Papachristou Georgios I, Slivka Adam, Zeh Herbert J, Zureikat Amer H, Lee Kenneth K, Tsung Allan, Mantha Geeta S, Khalid Asif

Abstract excerpt

PURPOSE: Management guidelines for pancreatic intraductal papillary mucinous neoplasms (IPMN) and mucinous cystic neoplasms (MCN) are based on the assumption that mucinous cysts can be accurately distinguished from other pancreatic cystic lesions. Previous studies using surgical material have identified recurrent mutations in GNAS and KRAS in pancreatic mucinous neoplasms. Yet, the diagnostic utility of testing...

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Share to Adenocarcinoma, Mucinous
Share to Biopsy, Fine-Needle

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Carcinoma, Pancreatic Ductal

Share to Carcinoma, Papillary

Share to Chromogranins

Share to GTP-Binding Protein alpha Subunits, Gs

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Source

Identifiers

PMID: 24938521
DOI: 10.1158/1078-0432.CCR-14-0513

Genes

GNAS
KRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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