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Article

Clinical Impact of KRAS and GNAS Analysis Added to CEA and Cytology in Pancreatic Cystic Fluid Obtained by EUS-FNA.

Digestive diseases and sciences - 1 Sept 2018

Faias Sandra, Duarte Marlene, Albuquerque Cristina, da Silva João Pereira, Fonseca Ricardo, Roque Ruben, Dias Pereira Antonio, Chaves Paula, Cravo Marília

Abstract excerpt

BACKGROUND: Pancreatic cysts are common incidental findings with malignant potential, raising diagnostic and treatment dilemmas. AIMS: To determine the added value of KRAS and GNAS mutation analysis on cyst classification and decision making. METHODS: We analyzed 52 frozen samples of pancreatic cystic fluid obtained by EUS-FNA between 2008 and 2014. In addition to cytology and CEA, mutations of GNAS (exons 8 and...

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Carcinoembryonic Antigen
Carcinoma
Chromogranins
Endoscopic Ultrasound-Guided Fine Needle Aspiration
GTP-Binding Protein alpha Subunits, Gs

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Neoplasms, Cystic, Mucinous, and Serous

Pancreatic Neoplasms

Proto-Oncogene Proteins p21(ras)

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Identifiers

PMID: 29796909
DOI: 10.1007/s10620-018-5128-y

Genes

KRAS
GNAS

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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