Article
Gain-of-function mutations in FcgammaRI of NOD mice: implications for the evolution of the Ig superfamily.
The EMBO journal - 15 Jul 1998
Gavin A L, Tan P S, Hogarth P M
Abstract excerpt
It has been postulated that, during evolution of the Ig superfamily, modifications of the function of individual receptors might occur by acquisition of exons and their subsequent modification, though evidence of this is lacking. Here we have analysed the interaction of mouse IgG subclasses with high-affinity FcgammaRI (CD64) which contains three Ig-like domains and is important in innate and adaptive immunity....
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