Article
Mouse FcgammaRI: identification and functional characterization of five new alleles.
Immunogenetics - 1 Mar 2000
Gavin A L, Leiter E H, Hogarth P M
Abstract excerpt
The mouse Fcgr1 gene encoding the high-affinity IgG receptor (FcgammaRI) exists as two known alleles, FcgammaRI-BALB and FcgammaRI-NOD, and these alleles exhibit functional differences. To determine whether other alleles exist in mouse strains, Fcgr1 coding regions from 35 strains of mice were sequenced and a further five alleles were identified. The FcgammaRI-BALB and NOD alleles are now designated the "a" and...
Topics
- Alleles
- Amino Acid Sequence
- Animals
- Base Sequence
- COS Cells
- DNA, Complementary
- Mice
- Mice, Inbred BALB C
- Mice, Inbred NOD
- Mice, Inbred Strains
- Molecular Sequence Data
- Receptors, IgG
- Sequence Homology, Amino Acid
- Sequence Homology, Nucleic Acid