Comparative neuropathology of Kuru with the new variant of Creutzfeldt-Jakob disease: evidence for strain of agent predominating over genotype of host.

doi:10.1111/j.1750-3639.1998.tb00165.x

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Article

Comparative neuropathology of Kuru with the new variant of Creutzfeldt-Jakob disease: evidence for strain of agent predominating over genotype of host.

Brain pathology (Zurich, Switzerland) - 1 Jul 1998

McLean C A, Ironside J W, Alpers M P, Brown P W, Cervenakova L, Anderson R M, Masters C L

Abstract excerpt

The three major influences on the phenotype of the transmissible spongiform encephalopathies are believed to be strain of agent, route of infection and host genotype. We have compared the pathologic profiles and genotypes of the new variant of Creutzfeldt-Jakob disease (vCJD) and kuru. The compar...

Topics

Adolescent
Adult
Creutzfeldt-Jakob Syndrome
DNA
Female
Genotype
Humans
Immunoenzyme Techniques
Kuru
Male
Middle Aged
Prions

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