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Article

Molecular analysis of prion strain variation and the aetiology of 'new variant' CJD.

Nature - 24 Oct 1996

Collinge J, Sidle K C, Meads J, Ironside J, Hill A F

Abstract excerpt

Strains of transmissible spongiform encephalopathies are distinguished by differing physicochemical properties of PrPSc, the disease-related isoform of prion protein, which can be maintained on transmission to transgenic mice. 'New variant' Creutzfeldt-Jakob disease (CJD) has strain characteristics distinct from other types of CJD and which resemble those of BSE transmitted to mice, domestic cat and macaque,...

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PMID: 8878476
DOI: 10.1038/383685a0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Molecular analysis of prion strain variation and the aetiology of 'new variant' CJD.PMID 8878476Read ↗

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