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Article

Aberrant expression of ETS1 and ETS2 proteins in cancer

1 Jan 2018

Abstract excerpt

The ETS transcription factors regulate expression of genes involved in normal cell development, proliferation, differentiation, angiogenesis, and apoptosis, consisting of 28 family members in humans. Dysregulation of these transcription factors facilitates cell proliferation in cancers, and several members participate in invasion and metastasis by activating gene transcription. ETS1 and ETS2 are the founding...

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PMID: 29974077
DOI: 10.15761/crr.1000151

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