Article
Genetic polymorphism and Parkinson's disease in Taiwan: study of debrisoquine 4-hydroxylase (CYP2D6).
Journal of the neurological sciences - 11 Jun 1998
Lo H S, Chen C H, Hogan E L, Kao K P, Wang V, Yan S H
Abstract excerpt
Debrisoquine 4-hydroxylase (CYP2D6) is one of the cytochrome P450 enzyme families that catalyze the breakdown of a variety of exogenous and endogenous compounds. Previous reports have suggested that genetic polymorphisms of debrisoquine 4-hydroxylase are associated with susceptibility to Parkinso...
Topics
- Adult
- Aged
- Aged, 80 and over
- Alleles
- Asian People
- Cytochrome P-450 CYP2D6
- Disease Susceptibility
- Female
- Genotype
- Humans
- Male
- Middle Aged
- Nerve Tissue Proteins
- Parkinson Disease
- Point Mutation
- Polymerase Chain Reaction
- Polymorphism, Restriction Fragment Length
- Taiwan