Article
Parkinson's disease and CYP2D6 polymorphism in Asian populations: A meta-analysis.
Neuroepidemiology - 1 Jan 2000
Persad Amanda S, Stedeford Todd, Tanaka Seigo, Chen Liping, Banasik Marek
Abstract excerpt
Polymorphism of CYP2D6 and its relationship with the development of Parkinson's disease (PD) has been controversial. The distribution of the B-mutation of CYP2D6, a mutation that results in the absence of a functional protein, differs by ethnicity and accounts for less than 1% of the 'poor metabolizer' phenotype in Asians. Thus, a meta-analysis was conducted to determine if polymorphism, other than the...
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